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Description

rivotril 2 mg clonazepam

rivotril 2 mg clonazepam contains a medicine called clonazepam. This belongs to a group of
medicines called ‘benzodiazepines’.
Rivotril is used to treat epilepsy in infants, children and adults.
• It lowers the number of fits (seizures) that you have.
• Any fits that you do have will be less serious.

made by Laboratoire(s), ROCHE.

CLINICAL PHARMACOLOGY

Pharmacodynamics: The precise mechanism by which clonazepam exerts its antiseizure
and antipanic effects is unknown, although it is believed to be related to its ability to
enhance the activity of gamma aminobutyric acid (GABA), the major inhibitory
neurotransmitter in the central nervous system.

Convulsions produced in rodents by
pentylenetetrazol or, to a lesser extent, electrical stimulation are antagonized, as are
convulsions produced by photic stimulation in susceptible baboons. A taming effect in
aggressive primates, muscle weakness and hypnosis are also produced. In humans,
clonazepam is capable of suppressing the spike and wave discharge in absence seizures
(petit mal) and decreasing the frequency, amplitude, duration and spread of discharge in
minor motor seizures.

Pharmacokinetics:

Clonazepam is rapidly and completely absorbed after oral
administration. The absolute bioavailability of clonazepam is about 90%. Maximum
plasma concentrations of clonazepam are reached within 1 to 4 hours after oral
administration. Clonazepam is approximately 85% bound to plasma proteins.
Clonazepam is highly metabolized, with less than 2% unchanged clonazepam being
excreted in the urine.

Biotransformation occurs mainly by reduction of the 7-nitro group to the 4-amino derivative. This derivative can be acetylated, hydroxylated and
glucuronidated. Cytochrome P-450 including CYP3A, may play an important role in
clonazepam reduction and oxidation. The elimination half-life of clonazepam is typically
30 to 40 hours. Clonazepam pharmacokinetics are dose-independent throughout the
dosing range. There is no evidence that clonazepam induces its own metabolism or that
of other drugs in humans.

INDICATIONS AND USAGE

Seizure Disorders: Klonopin is useful alone or as an adjunct in the treatment of the
Lennox-Gastaut syndrome (petit mal variant), akinetic and myoclonic seizures. In
patients with absence seizures (petit mal) who have failed to respond to succinimides,
Klonopin may be useful.

In some studies, up to 30% of patients have shown a loss of anticonvulsant activity, often
within 3 months of administration. In some cases, dosage adjustment may reestablish
efficacy.

Panic Disorder:

rivotril 2 mg clonazepam is indicated for the treatment of panic disorder, with or
without agoraphobia, as defined in DSM-IV. Panic disorder is characterized by the
occurrence of unexpected panic attacks and associated concern about having additional
attacks, worry about the implications or consequences of the attacks, and/or a significant
change in behavior related to the attacks.

CONTRAINDICATIONS

Klonopin should not be used in patients with a history of sensitivity to benzodiazepines,
nor in patients with clinical or biochemical evidence of significant liver disease. It may
be used in patients with open angle glaucoma who are receiving appropriate therapy but
is contraindicated in acute narrow angle glaucoma.

rivotril 2 mg clonazepam
rivotril 2 mg clonazepam

What rivotril 2 mg clonazepam is and what it is used for

rivotril 2 mg clonazepam contains a medicine called clonazepam. This belongs to a group of
medicines called ‘benzodiazepines’.
Rivotril is used to treat epilepsy in infants, children and adults.

  1.  It lowers the number of fits (seizures) that you have.
  2. Any fits that you do have will be less serious.

Before you take Rivotril

Do not take Rivotril if you are allergic (hypersensitive) to:

  1. • Clonazepam or any of the other ingredients of Rivotril (listed in Section 6:
    Further information).
  2. Other ‘benzodiazepine’ medicines. These include diazepam, flurazepam and temazepam. Do not take Rivotril if any of the above apply to you. If

What Clonazepam looks like and contents of the pack

  1.  Clonazepam 0.5mg Tablets are round, pinkish-buff in colour, marked Roche 0.5 on one side and a break line on the other.
  2. Clonazepam 2mg Tablets are round, white in colour, marked Roche 2 on one side and two break lines on the other.
  3. Clonazepam tablets have break lines so that they can easily be broken into halves or quarters so that you can take low doses at the start of your treatment.
  4. Clonazepam tablets are supplied in blisters packs of 60 tablets.

What Clonazepam contains

The active substance in Clonazepam is clonazepam.
• Clonazepam 0.5mg Tablets. Each tablet contains 0.5mg clonazepam. The other ingredients in Clonazepam 0.5mg Tablets are lactose monohydrate, maize starch, pregelatinised potato starch, talc, magnesium stearate, yellow iron oxide (E172) and red iron oxide (E172).
• Clonazepam 2mg Tablets. Each tablet contains 2mg clonazepam. The other ingredients Clonazepam 2mg Tablets are lactose anhydrous, maize starch, microcrystalline cellulose and magnesium stearate.

How to store Clonazepam

  1. Store in the original blister and outer carton in order to protect from light.
  2.  Keep out of the sight and reach of children.
  3. Do not use Clonazepam after the expiry date printed on the pack.
  4. Do not throw away any left-over tablets. Instead, return them to your pharmacist
  5. that they can be disposed of carefully. Only keep them if your doctor tells you to.
  6. If the tablets become discoloured or show any other signs of deterioration, you should seek the advice of your pharmacist who will tell you what to do.

How to take Clonazepam

Always take Clonazepam exactly as your doctor has told you. You should
check with your doctor if you are not sure.
• Your doctor will start you on a low dose of Clonazepam and gradually increase it over 2 to 4 weeks until the right dose has been found for you.
• Your doctor will usually tell you to split your daily dose into three equal amounts which you will take at evenly spaced times throughout the day.
• If the daily dose cannot be split equally, take the largest dose at bedtime.
• Once your doctor has found the right dose for you, they may tell you to take Clonazepam as a single dose in the evening.

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1 review for rivotril 2 mg clonazepam buy rivotril 2 mg top pills online

  1. Karmel

    My lovely benzo

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